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  "Title": "Given a List of Gene Symbols, Performs Differential Enrichment\nAnalysis",
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  "Authors@R": "c(person(given = \"Harry\",\nfamily = \"Smith\",\nrole = c(\"aut\", \"cre\"),\nemail = \"harry.smith@ucdenver.edu\"),\nperson(given = \"Laura\",\nfamily = \"Saba\",\nrole = \"aut\",\nemail = \"laura.saba@ucdenver.edu\"))",
  "Description": "Compare functional enrichment between two\nexperimentally-derived groups of genes or proteins (Peterson,\nDR., et al.(2018)) <doi: 10.1371/journal.pone.0198139>. Given a\nlist of gene symbols, 'diffEnrich' will perform differential\nenrichment analysis using the Kyoto Encyclopedia of Genes and\nGenomes (KEGG) REST API. This package provides a number of\nfunctions that are intended to be used in a pipeline. Briefly,\nthe user provides a KEGG formatted species id for either human,\nmouse or rat, and the package will download and clean species\nspecific ENTREZ gene IDs and map them to their respective KEGG\npathways by accessing KEGG's REST API. KEGG's API is used to\nguarantee the most up-to-date pathway data from KEGG. Next, the\nuser will identify significantly enriched pathways from two\ngene sets, and finally, the user will identify pathways that\nare differentially enriched between the two gene sets. In\naddition to the analysis pipeline, this package also provides a\nplotting function.",
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      "modified": "2022-06-27 17:14:51",
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